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Veterinarian Recommended. ZYMOX Topical Cream with 0.5% Hydrocortisone Promotes healthy skin and provides relief from itching caused by inflammation, dermatitis, and other minor skin irritations. ZYMOX Topical Cream contains the patented LP3 Enzyme System which blends a concentrated combination of protein, enzymes plus skin soothing aloe vera and 0.5% hydrocortisone for itch relief. The Cream features a catheter tip for direct application. Ideal for areas around the face, paws, and body folds.