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PURINA PRO PLAN Calming Care contains a blend of probiotics to help dogs stay calm. This therapeutic diet was developed by Purina nutritionists, researchers, and veterinarians. It may take up to six weeks for this formula to show results.

Features:

• Using the probiotic strain BL999 to help dogs maintain calm behavior
• For dogs with anxious behaviors such as excessive vocalization, jumping, pacing and spinning
• Help dogs cope with stress such as brief separation from their owners, unfamiliar visitors, novel sounds, or changes in their daily activities and location
• Helps dogs maintain a normal heartbeat during stressful events
• Help dogs manage their emotions and maintain a healthy immune system
• High palatability and delicious
• Each pack contains 1X109 CFU of the probiotic strain Bifidobacterium longum (BL999) to help maintain a stable mood

: Understanding Dog Emotional Health

Frequently Asked Questions:

Q: How does PRO PLAN CALMING CARE mood-stabilizing probiotics stabilize dogs’ emotions?

A: Mood-stabilizing probiotics, utilizing a bacterial strain called Bifidobacterium longum (BL999), have been shown to help dogs and cats maintain calm behavior. Diet-related changes in the gut microbiome can influence the brain through the gut-brain axis, which in turn can impact behaviors including anxiety.

In clinical validation, BL999 produced a significant improvement in anxiety behaviors in dogs, with dogs and cats given BL999 as a supplement showing improvements in behaviors compared to placebo. This included:

• Improve dogs that display anxious behaviors such as excessive vocalization, jumping, and wandering
• Maintains normal heart activity during stressful events.
• Slows down the cortisol response to anxiety-inducing events.

Q: How long does it take for PRO PLAN CALMING CARE Mood Stabilizing Probiotics to be effective?

A: Studies have shown that using one pack of Calming Care daily for six weeks produces results. Calming Care should be used daily, not just as a short-term anti-anxiety solution for occasional stressful events, such as routine and environmental changes, but as part of a behavioral and environmental modification approach.

Q: Is there any scientific research supporting the effectiveness of PRO PLAN CALMING CARE Mood Stabilizing Probiotics?

A: Purina evaluated the effects of BL999 on anxiety-prone behaviors in dogs and presented an abstract at the 2018 American College of Veterinary Behavioral Medicine Symposium. The paper has been submitted for publication. Additionally, researchers at Colorado State University evaluated the effects of BL999 on anxiety-prone behaviors in cats and presented an abstract at the 2021 American Academy of Veterinary Internal Medicine Forum.